前两天看了ABCC9的两篇科普报道,一个来源是BBC的,果壳引用了一下(http://www.guokr.com/article/77670/; BBC英文链接http://www.bbc.co.uk/news/health-15999489),说ABCC9基因携带者平均要多睡30分钟……另一篇原文是Science Daily的,说ABCC9基因携带者平均要少睡一些(中文版:http://edu.sina.com.cn/en/2011-11-28/184963428.shtml;原文:http://www.sciencedaily.com/releases/2011/11/111124150237.htm),两篇报道引用的是同一篇paper,我找来看过之后发现基本上对非生物专业的孩子来说是天书……唯一比较接近人话的是这么一句:
We confirmed the conserved role of ABCC9 by knocking down its
homologue in Drosophila(果蝇), which shortened night time
but not daytime sleep duration.
但是knocking down ABCC9's homologue 是个什么过程呢……过两天有空写信问下作者好了……
———————2012.1.26补完——————
According to this paper ( http://www.nejm.org/doi/full/10.1056/NEJMp0707712), knock down homologue seems to be mute the homologue in the fruitfly by introduce some RNA.
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